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  • Rabies vaccinations

Rabies is a relatively rare, but dangerous viral infection, which attacks the brain and nervous system. It is carried by a variety of wild and domestic mammals, including dogs, cats, wolves, foxes, jackals, civets, mongooses, racoons and bats. The greatest risk in most countries is from domestic dogs, although vampire bats are a significant risk in parts of South America.

Rabies is usually transmitted to humans through the saliva of an infected animal, through bites, licking of broken skin or scratches. However, being spat in the face by a startled bat also counts as a significant exposure.
Rabies is especially common in parts of Africa, India, South East Asia and China, causing 59,000 human deaths each year and untold fear and suffering.

A recent outbreak in Bali, which until 2008 had been rabies-free, has so far claimed the lives of at least 160 people (and countless more dogs). The outbreak continues with 9 human deaths reported in the first 7 months of 2015 alone. Many hospitals on the island have now simply run out of rabies vaccine.

Overall, the risk to travellers is verysmall, but the consequences potentially major. Without vaccination, rabies is almost universally fatal.

By contrast the risk of a potentially rabid bite when travelling in an endemic country is relatively common!
It is now more than:

30x the risk of Hepatitis A
40 – 95x the risk of Hepatitis B
20x the risk of Typhoid in the Indian Subcontinent
63 – 400x the risk of Typhoid in Africa and South America

Prevention

  • Rabies vaccination is strongly recommended by the WHO for all travellers to regions where rabies is either moderately or highly endemic.
  • Unnecessary contact with dogs and other animals (including temple monkeys) should be avoided.
  • Vampire bats tend to feed from veins on the feet of sleeping people. A mosquito net is thus a sensible precaution at night in the Amazon.

Rabies vaccination

Pre-exposure vaccination consists of a course of three vaccinations, typically on days 0, 7 and 28.

Rabies vaccination can be given by either the intra-dermal or intra-muscular routes. Both are equally effective, but the intra-dermal route is cheaper and less painful. Dunfermline Travel Clinic is one of the only Fife travel clinics which offers intra-dermal vaccination.

The current Scottish and international guidelines are that no further, ‘routine’ boosters are required for most travellers following a full, intra-dermal or intra-muscular course, except in the event of a significant exposure (see below).

Treatment

what to do if you are bitten, scratched or spat in the eyes/mouth by a suspect animal:

  • Wash the wound out immediately with plenty of water or any other readily available fluid to remove any traces of saliva. (For eyes, just use water or contact lens solution.)
  • Follow this up with neat alcohol or povidone iodine (Betadine) solution if available to help disinfect the wound.
  • You should then seek medical attention locally as soon as possible for assessment by a doctor…

If you HAVE had three pre-exposure vaccines previously:

You would probably be advised by the doctor you see locally to have a booster. This would mean either four intra-dermal vaccinations on the same day, or two intra-muscular ones, three days apart. While the immunity from a full course is now considered to be life-long, it is generally thought safest practice to re-alert the immune system’s memory cells in the event of a possibly rabid bite.

No-one who has had a complete pre-exposure course, followed by a booster after an exposure has ever gone on to develop rabies. No other vaccine can compare with this 100% record!

If you HAVE NOT had a full, pre-exposure vaccination course:

You may need to have BOTH:

  • Human Rabies Immunoglobulin (HRIG)* injected around the wound as soon as possible,
    AND:
  • Five standard rabies vaccinations on days 0, 3, 7, 14 and 30 after exposure.

*Please note: HRIG is often in short supply in rabies-endemic countries, and where available, usually only in a major or capital city.

Expeditions and other ‘extremely remote’ travel:

Rabies vaccination is considered by most Expedition/Wilderness Medicine professionals to be a pre-requisite for people going on expedition to a high risk region. It can also work out more cost-effective to arrange this as a group.

For travellers planning to be in extremely remote areas (i.e. more than 48 hours away from a hospital) additional, special arrangements may be advisable, e.g. carrying a dose of rabies vaccine with you, or having a precautionary booster just before you travel. If you feel you might fall into this category, please speak to Jim to arrange training, supplies etc.

Rabies immunity testing

There are some people who have a high occupational risk of unnoticed rabies exposure, e.g. laboratory workers working with the virus, or people working with wild or stray animals.

For such people and/or for extra peace of mind, Dunfermline Travel Clinic offers a rabies immunity testing service. This consists of a simple blood test to see if you have significant levels of rabies neutralising antibody in your blood.

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Business Medical is based in Dunfermline, Fife and we operate throughout Central Scotland. For further information on our services please contact us by telephone or complete the enquiry form.

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